Top 10 Causes of Death for Americans Ages 20 to 24

Common causes of death in people aged 20-24 in the United States include illnesses, accidents, and conditions present at birth (congenital).

This article will go over the top 10 causes of death for young adults in the United States as of 2021 data collected by the Centers for Disease Control and Prevention (CDC), offer tips for how to prevent those that are preventable, and manage those that are not.

1

Unintentional Injuries

According to the CDC, unintentional injuries accounted for 43% of deaths among people aged 20-24 years old in 2021.

Many of these deaths were caused by poisonings related to certain drugs, including narcotics and hallucinogens. Drug poisoning can happen by accident, which is why properly storing and discarding medications is important.

However, some people who die from being exposed to these drugs have a substance use disorder. They may die from an overdose or from complications that happen when more than one substance is used at the same time.

In some cases, a person dies after using a substance that they didn’t realize had been mixed or “laced” with something else.

If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area.

Motor vehicle accidents also accounted for many accidental deaths, as they have in previous years. Although cars are getting safer, deaths caused by motor vehicle accidents are increasing. Traffic accident deaths were only very slightly down in 2022 following two years of sharp increases: 7.3% in 2020 and 10.1% in 2021.  

To protect yourself, wear your seat belt, drive defensively, and avoid risky behaviors (like driving while texting) when you’re behind the wheel.

2

Suicide

Suicide was the second leading cause of death among people ages 20-24 in 2021, accounting for 16.8% of deaths.

A person of any age can have suicidal thoughts, but there is a rising mental health crisis among youth in the U.S.

If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at 988 for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call 911

3

Homicide

Homicide, or murder, was the third-leading cause of death in 2021 and was responsible for 15.6% of deaths for people in the 20-24 age group. Most of these homicides were committed with firearms.

Reaching out for help if you’re experiencing domestic violence or if you are at risk of neighborhood gun violence are key steps that you can take.

If you have firearms in your home, it’s important that they are kept safely—particularly if you have children.

4

COVID-19

In 2021, 4.2% of deaths in people ages 20-24 were related to COVID-19.

As of 2021 data from the CDC, COVID has become the third-leading cause of death for all ages in the U.S. This is expected to decline, however, since most people have some immunity to the virus through exposure or vaccination.

People of any age who have certain risk factors, like obesity and underlying medical conditions, are more likely to die from or with COVID.

COVID can lead to death when the infection leads to complications like sepsis, blood clots, and organ failure, or if it affects respiratory function.

In some cases, COVID is considered a contributing cause of death. For example, a young person with cancer may have had cancer listed as their primary cause of death on their death certificate, but having had COVID was considered a contributing factor.

The best way to prevent COVID is to get vaccinated (and boosted) and take precautions, like masking and social distancing.

5

Cancer

Cancer (malignant neoplasms) caused about 2.9% of deaths in the 20-24 age group in 2021.

Although there is no definitive way to prevent cancer, you can reduce your risk. Some general steps you can take to support your overall health include:

  • Eating a nutritious diet
  • Staying physically active
  • Managing stress
  • Protecting your skin from the sun
  • Getting regular cancer screenings as recommended
  • Not smoking or using tobacco (or quitting if you do)

Talk to your provider about specific steps you can take to lower your risk for cancer. It is also important to know the early signs and symptoms of cancer so you can seek treatment in the early stages when you have the best possible chance of successful treatment.

6

Heart Disease

In 2021, about 2.5% of deaths in people ages 20-24 were from heart disease.

Many young people who have heart disease were born with it (congenital heart disease).

However, heart disease can also happen later in life—especially for people who have certain risk factors. You can take steps to lower your risk of heart disease at any age by:

  • Eating a balanced, heart-healthy diet
  • Getting exercise that raises your heart rate
  • Avoiding substances that are known to harm your heart, like tobacco and illicit drugs
  • Talking to your family to get a better sense of your genetic risk for heart disease
  • Seeing your provider for heart health check-ups, including knowing your cholesterol levels and blood pressure
  • Trying your best to manage stress
7

Diabetes Mellitus

Diabetes caused about 1.0% of deaths among people ages 20 to 24 in 2021.

People with diabetes live longer now than they used to because of advances in how the disease is treated. However, it can still cause complications.

For example, having diabetes increases your risk of having heart attacks and strokes.

Both type 1 and type 2 diabetes have been found to have a genetic predisposition, as well as environmental triggers.

For example, managing the condition is important by making sure the necessary insulin needed to survive is on hand and making any lifestyle changes necessary to stay healthy.

People with type 2 diabetes can also manage the condition through lifestyle changes and, in some cases, medication.

In many cases, the condition can be prevented by taking certain steps. Some of these steps can also reverse type 2 diabetes.

You might be able to lower your risk of type 2 diabetes or reverse it by:

8

Congenital Abnormalities

Congenital conditions (also called anomalies) are those that people are born with. In 2021, these conditions accounted for 0.9% of deaths among people ages 20-24.

One example of this type of condition is cystic fibrosis.

Since these conditions happen before a person is born, people who are pregnant can be screened to find out if a fetus is at risk for certain conditions.

For someone living with a congenital condition, preventing complications comes down to learning how to manage the condition and having a team of providers that they can work with.

9

Complicated Pregnancy

About 0.7% of deaths among people ages 20-24 occurred during pregnancy or during/after childbirth.

There are several reasons that people can die during pregnancy or while giving birth, including:

You can’t always control whether these complications happen to you. However, there are some general steps that you can take to lower the chances that they’ll happen, such as:

  • Getting routine medical care during your pregnancy
  • Taking your prenatal vitamins (with folic acid) as recommended by your healthcare provider
  • Exercising in ways that are comfortable and safe for you
  • Getting plenty of good quality sleep
  • Staying up to date on your vaccinations, including the annual flu shot and COVID-19 vaccines/boosters
  • Knowing the signs and symptoms of complications (such as unusual bleeding or high blood pressure) and contacting your provider right away if you feel unwell
10

Cerebrovascular Diseases

In 2021, cerebrovascular diseases accounted for about 0.5% of deaths among people between the ages of 20-24.

Examples of these conditions include:

There are some steps you can take to reduce your risk of developing these conditions and prevent complications from them, such as:

  • Not smoking, quitting if you do use tobacco, and avoiding second-hand smoke
  • Reducing alcohol intake
  • Keeping your blood pressure controlled through lifestyle changes
  • Following your prescribed treatment plan
Top 10 Causes of Death, 20-24 Year Olds (2021)
Causes % Prevention
Unintentional Injuries 43.0% Avoid illicit drugs, wear a seat belt, drive safely
Suicide 16.8% Seek mental health support
Homicide 15.6% Reach out for help if in a dangerous situation; keep guns at home safely locked up.
COVID-19 4.2% Get vaccinated and boosted and take precautions like wearing a mask and social distancing
Cancer 2.9% Know your family history/genetic risk, make lifestyle changes to reduce risk, get screenings
Heart disease 2.5% Follow a heart-healthy lifestyle, keep blood pressure and cholesterol in check, exercise
Diabetes 1.0% Cannot be prevented but can be managed; if pregnant, get screened for genetic conditions if recommended
Congenital Conditions 0.9% Make lifestyle changes, manage your weight, take medications as prescribed
Pregnancy and Childbirth 0.7% Get routine prenatal care, know the signs of possible complications, get adequate nutrition/supplements if needed
Cerebrovascular Diseases 0.5% Keep blood pressure and cholesterol in check, exercise
All other causes 12.0%

Summary

Many potential causes of death at any age are out of your control. However, by adopting a healthy lifestyle and practicing safety measures, many of them can be prevented. Seeing your primary care provider for regular visits is also recommended.

Even if you can’t prevent a disease, you often can reduce your risk of complications from it—including death. Talk to your provider about your risks and work together on lowering them.

Frequently Asked Questions

15 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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  9. Elezkurtaj S, Greuel S, Ihlow J, et al. Causes of death and comorbidities in hospitalized patients with COVID-19Scientific Reports. 2021;11(1). doi:10.1038/s41598-021-82862-5

  10. Centers for Disease Control and Prevention. COVID-19 as the underlying or contributing cause of death.

  11. National Cancer Institute. Cancer prevention overview (PDQ)-Patient version.

  12. World Health Organization. Diabetes.

  13. American Diabetes Association. Genetics of diabetes.

  14. American Heart Association. 5 critical steps to help prevent a stroke.

  15. American Cancer Society. Types of cancers that develop in young adults.

By Mark Stibich, PhD
Mark Stibich, PhD, FIDSA, is a behavior change expert with experience helping individuals make lasting lifestyle improvements.